Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037136 | 0.92 | PREP (0.55) | KLK7MEN1KMT2AFKBP1APREP | |
| SCHEMBL9037131 | 0.92 | PREP (0.55) | KLK7MEN1KMT2AFKBP1APREP | |
| SCHEMBL9037028 | 0.88 | PREP (0.54) | KMT2APREPACE2 | |
| SCHEMBL344678 | 0.87 | ABCB1 (0.48) | KLK7PARP1MEN1KMT2AHTT | |
| SCHEMBL344679 | 0.87 | ABCB1 (0.48) | KLK7PARP1MEN1KMT2AHTT | |
| SCHEMBL25449146 | 0.87 | PRMT5 (0.47) | KLK7PARP1MEN1KMT2AFKBP1A | |
| SCHEMBL3431999 | 0.84 | PREP (0.46) | FKBP1APREP | |
| SCHEMBL7908488 | 0.84 | KLK7 (0.52) | KLK7PARP1MEN1KMT2AFKBP1A | |
| SCHEMBL4664791 | 0.84 | KLK7 (0.52) | KLK7PARP1MEN1KMT2AFKBP1A | |
| SCHEMBL7908485 | 0.84 | KLK7 (0.52) | KLK7PARP1MEN1KMT2AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |