Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037131 | 1.00 | PREP (0.55) | PREPKLK7MEN1KMT2AHSD17B10 | |
| SCHEMBL9037209 | 0.92 | KLK7 (0.51) | PREPKLK7MEN1KMT2AFKBP1A | |
| SCHEMBL9610764 | 0.85 | KLK7 (0.61) | PREPKLK7MEN1KMT2AHSD17B10 | |
| SCHEMBL7307432 | 0.85 | KLK7 (0.61) | PREPKLK7MEN1KMT2AHSD17B10 | |
| SCHEMBL9609458 | 0.85 | KLK7 (0.61) | PREPKLK7MEN1KMT2AHSD17B10 | |
| SCHEMBL6925800 | 0.84 | FKBP1A (0.64) | PREPKLK7MEN1KMT2AFKBP1A | |
| SCHEMBL5248179 | 0.83 | KLK7 (0.56) | PREPKLK7MEN1KMT2AFKBP1A | |
| SCHEMBL5970730 | 0.83 | KLK7 (0.66) | PREPKLK7MEN1KMT2AFKBP1A | |
| SCHEMBL159104 | 0.83 | KLK7 (0.66) | PREPKLK7MEN1KMT2AFKBP1A | |
| SCHEMBL159105 | 0.83 | KLK7 (0.66) | PREPKLK7MEN1KMT2AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |