Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.55 |
| ▸ | NOS3 | P29474 | 8/20 | 0.55 |
| ▸ | NOS2 | P35228 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961521 | 0.91 | NOS1 (0.54) | NOS1NOS3NOS2 | |
| SCHEMBL9040771 | 0.86 | NOS3 (0.65) | NOS1NOS3NOS2 | |
| Bromide SCHEMBL6962685 | 0.85 | NOS3 (0.66) | NOS1NOS3NOS2 | |
| SCHEMBL6967530 | 0.85 | NOS1 (0.53) | NOS1NOS3NOS2 | |
| SCHEMBL5378871 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2 | |
| SCHEMBL5378876 | 0.81 | NOS1 (0.64) | NOS1NOS3NOS2 | |
| SCHEMBL9038303 | 0.80 | NOS1 (0.69) | NOS1NOS3NOS2 | |
| SCHEMBL6966862 | 0.79 | NOS1 (0.65) | NOS1NOS3NOS2 | |
| SCHEMBL4484844 | 0.79 | NOS1 (0.57) | NOS1NOS3NOS2 | |
| Bromide SCHEMBL6967212 | 0.79 | NOS1 (0.68) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071746-C | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 2001-09-26 | — | — | CN | claimed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | claimed |
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | claimed |