Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039718 | 0.89 | BDKRB1 (0.35) | BDKRB1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9038326 | 0.84 | BDKRB1 (0.35) | BDKRB1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7838761 | 0.75 | MEN1 (0.39) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL7511908 | 0.75 | MAPT (0.34) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL9040554 | 0.75 | HRAS (0.36) | BDKRB1MAPT | |
| SCHEMBL7511634 | 0.74 | PRKD1 (0.32) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL7645811 | 0.73 | TOP1 (0.37) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL7506794 | 0.72 | MAPT (0.36) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL7507389 | 0.72 | MAPT (0.36) | MEN1ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL9039586 | 0.71 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722446-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996005196-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA S.P.A. (IT) | 1996-02-22 | — | — | WO | disclosed |