Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039718 | 0.80 | BDKRB1 (0.35) | ALDH1A1MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL7825842 | 0.78 | BDKRB1 (0.34) | — | |
| SCHEMBL7837931 | 0.78 | BDKRB1 (0.32) | — | |
| SCHEMBL8443434 | 0.78 | GRM1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7814609 | 0.77 | GRM1 (0.34) | — | |
| SCHEMBL8444844 | 0.76 | GRM1 (0.32) | — | |
| SCHEMBL9038411 | 0.73 | BDKRB1 (0.32) | HTT | |
| SCHEMBL7837827 | 0.72 | — | — | |
| SCHEMBL9037367 | 0.71 | BDKRB1 (0.32) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL9041188 | 0.70 | ALDH1A1 (0.34) | ALDH1A1HTTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722446-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996005196-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA S.P.A. (IT) | 1996-02-22 | — | — | WO | disclosed |