SCHEMBL9037487

SCHEMBL9037487

COC(=O)CSc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 19/20 0.50
BCAT2 O15382 17/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9036189 0.80 PPOX (0.34)
SCHEMBL10532221 0.79 BCAT1 (0.56) BCAT1BCAT2
SCHEMBL28887933 0.79 BCAT1 (0.48) BCAT1BCAT2
SCHEMBL10576815 0.77 BCAT1 (0.78) BCAT1BCAT2
SCHEMBL7901260 0.76 KMT2A (0.35)
SCHEMBL9423008 0.76 BCAT1 (0.53) BCAT1BCAT2
SCHEMBL13842893 0.75 BCAT1 (0.59) BCAT1BCAT2
SCHEMBL22720001 0.75 BCAT1 (0.51) BCAT1BCAT2
SCHEMBL7682453 0.75 BCAT1 (0.50) BCAT1BCAT2
SCHEMBL5393246 0.75 BCAT1 (0.54) BCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408382-B1 Uracil derivatives and herbicides containing the same as active ingredient NISSAN CHEMICAL IND LTD (JP) 1996-09-18 EP disclosed
US-5127935-A Halogen, phenyl and heterocycle substituents, agricultural use NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-07-07 US disclosed
US-5084084-A Uracil and thiouracil derivatives NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-01-28 US disclosed
EP-0408382-A2 Uracil derivatives and herbicides containing the same as active ingredient NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1991-01-16 EP disclosed