Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036169 | 0.90 | GFER (0.58) | GFERHTTMAPK14DRD2DRD3 | |
| SCHEMBL8923783 | 0.88 | GFER (0.42) | GFERHTTMAPK14HDAC1HDAC6 | |
| SCHEMBL9038015 | 0.88 | ALDH1A1 (0.47) | GFERHTTHDAC1HDAC6GAA | |
| SCHEMBL9037485 | 0.87 | GFER (0.55) | GFERHTTMAPK14DRD2DRD3 | |
| SCHEMBL9037801 | 0.87 | GFER (0.55) | GFERHTTMAPK14DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9001495 | 0.87 | ALDH1A1 (0.46) | GFERHTTHDAC1HDAC6GAA | |
| SCHEMBL9038867 | 0.86 | AVPR1A (0.43) | GFERHTTMAPK14DRD2DRD3 | |
| SCHEMBL9037247 | 0.86 | AVPR1A (0.43) | GFERHTTMAPK14GAAMEN1 | |
| SCHEMBL8985883 | 0.86 | ALDH1A1 (0.50) | GFERDRD2DRD3MEN1ALDH1A1 | |
| SCHEMBL9038022 | 0.85 | GFER (0.53) | GFERHTTMAPK14DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-B1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | UPJOHN CO (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |