Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038015 | 0.89 | ALDH1A1 (0.47) | GFERADRA2AADORA3CHRM1MAOA | |
| SCHEMBL5109661 | 0.88 | ADRA2A (0.53) | GFERADRA2AADORA3CHRM1MAOA | |
| Hydrochloric Acid SCHEMBL9001495 | 0.88 | ALDH1A1 (0.46) | GFERADRA2AADORA3CHRM1MAOA | |
| SCHEMBL9037637 | 0.88 | GFER (0.56) | GFERNPSR1GAAALDH1A1HPGD | |
| SCHEMBL8985883 | 0.88 | ALDH1A1 (0.50) | GFERNPSR1ALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL8985797 | 0.87 | ALDH1A1 (0.49) | GFERNPSR1ALDH1A1HSD17B10HPGD | |
| SCHEMBL8922978 | 0.86 | TNFSF11 (0.57) | TNFSF11TNFKMT2AHTT | |
| SCHEMBL8923153 | 0.84 | TRPV1 (0.47) | KCNH2NPSR1HSD17B10 | |
| SCHEMBL9038867 | 0.82 | AVPR1A (0.43) | GFERADRA2AADORA3CHRM1MAOA | |
| SCHEMBL9037247 | 0.82 | AVPR1A (0.43) | GFERADRA2AADORA3CHRM1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1993001181-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |