Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034117 | 0.98 | HTR1A (0.58) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9043516 | 0.97 | HTR1A (0.57) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| SCHEMBL9035223 | 0.97 | HTR1A (0.57) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9036002 | 0.96 | HTR1A (0.56) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| SCHEMBL9458358 | 0.93 | HTR1A (0.52) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458396 | 0.92 | HTR1A (0.51) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9035834 | 0.91 | HTR1A (0.57) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9035153 | 0.91 | HTR1A (0.57) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| SCHEMBL9458072 | 0.91 | HTR1A (0.54) | HTR1AADRA1BADRA1DADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458352 | 0.90 | HTR1A (0.53) | HTR1AADRA1BADRA1DADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422134-B1 | 5-HT SELECTIVE AGENTS | ABBOTT LAB (US) | 1996-06-12 | — | — | EP | claimed |