Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12881421 | 1.00 | TSHR (0.45) | TSHRSLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL12881466 | 1.00 | TSHR (0.45) | TSHRSLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL12881447 | 0.76 | TSHR (0.41) | TSHRSLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL19047014 | 0.72 | TSHR (0.37) | TSHRSLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL21597984 | 0.72 | TSHR (0.41) | TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL8128459 | 0.71 | SMN1; SMN2 (0.41) | TSHRSLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL7294639 | 0.71 | SMN1; SMN2 (0.41) | TSHRSLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL11288518 | 0.71 | ALDH1A1 (0.45) | TSHRSLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL8501615 | 0.70 | ALDH1A1 (0.46) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9666098 | 0.70 | ESR1 (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243769-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE FLUOROAMINE | CENTRAL GLASS CO LTD (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-8426645-B2 | Process for production of optically active fluoroamine | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8426645-B2 | Process for production of optically active fluoroamine | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20110034732-A1 | Process for Production of Optically Active Fluoroamine | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20110034732-A1 | Process for Production of Optically Active Fluoroamine | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2243769-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE FLUOROAMINE | Central Glass Company, Limited (JP) | 2010-10-27 | — | — | EP | disclosed |
| EP-0696283-A1 | 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- AND/OR 10-SUBSTITUTED DIBENZOXAZEPINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SEARLE & CO (US) | 1996-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034732-A1 | Process for Production of Optically Active Fluoroamine | PHF2, HNMT, PHF8 | TSHR 1945/4885SLC6A2 1284/4885ADRA1A 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.