Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 8/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27575342 | 1.00 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL4029191 | 0.80 | HDAC3 (0.38) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL8116292 | 0.76 | SLC6A3 (0.48) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL497951 | 0.75 | DPP4 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4987791 | 0.74 | KMT2A (0.44) | HSD11B1MAOBMAOA | |
| SCHEMBL29259636 | 0.74 | SLC6A3 (0.52) | SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL11904242 | 0.74 | MAOB (0.36) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL11904240 | 0.74 | MAOB (0.36) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB | |
| SCHEMBL5467676 | 0.73 | GRIN2D (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL19093772 | 0.73 | ESR1 (0.60) | SLC6A3SLC6A4SLC6A2HSD11B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495982-B1 | BICYCLIC PYRIMIDINE DERIVATIVE, METHOD OF PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5378700-A | Against hypoxemia of respiratory diseases | TEIJIN LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0495982-A1 | BICYCLIC PYRIMIDINE DERIVATIVE, METHOD OF PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |