Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623669 | 0.80 | FFAR1 (0.43) | RAB9ANPC1MAPTKDM4EGAA | |
| SCHEMBL623670 | 0.79 | RAB9A (0.47) | LTA4HMAPK14RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL25353224 | 0.78 | KCNH2 (0.44) | RAB9ASMN1; SMN2NPC1KCNH2MAPT | |
| SCHEMBL931875 | 0.77 | PTPRC (0.59) | RAB9ASMN1; SMN2NPC1KCNH2MAPT | |
| SCHEMBL623870 | 0.77 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2NPC1MAPTL3MBTL1 | |
| SCHEMBL4666391 | 0.77 | BACE1 (0.46) | LTA4HMAPK14RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12474061 | 0.77 | NMT1 (0.43) | KCNH2MAOAMAOBKDM1ACYSLTR2 | |
| SCHEMBL623871 | 0.77 | NPC1 (0.45) | RAB9ASMN1; SMN2NPC1MAOBL3MBTL1 | |
| SCHEMBL8357655 | 0.77 | NPC1 (0.47) | LTA4HMAPK14RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL23456171 | 0.76 | F2 (0.52) | RAB9ASMN1; SMN2NPC1KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385634-B1 | Process for producing pyrido[1,2-a] pyrimidine derivative | WAKO PURE CHEM IND LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5081243-A | Process for producing 3-tetrazolyl pyrido[1,2-a]pyrimidine derivatives | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0385634-A2 | Process for producing pyrido[1,2-a] pyrimidine derivative | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-09-05 | — | — | EP | disclosed |