Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6967439 | 0.98 | NPC1 (0.49) | NPC1RAB9AHPGDHDAC1PLAU | |
| SCHEMBL6968097 | 0.83 | KDM4E (0.60) | NPC1RAB9AHPGDHDAC1HDAC2 | |
| SCHEMBL6968442 | 0.81 | HPGD (0.59) | NPC1RAB9AHPGDHDAC1L3MBTL1 | |
| SCHEMBL6963445 | 0.81 | MEN1 (0.49) | NPC1RAB9AHPGDL3MBTL1POLB | |
| SCHEMBL10389709 | 0.80 | POLB (0.64) | NPC1RAB9AHDAC1PLAUHDAC2 | |
| SCHEMBL8148056 | 0.80 | POLB (0.49) | NPC1RAB9AHPGDL3MBTL1POLB | |
| SCHEMBL6966981 | 0.79 | HPGD (0.57) | NPC1HPGDHDAC1HDAC2HDAC3 | |
| SCHEMBL9218989 | 0.79 | MEN1 (0.45) | NPC1RAB9AHPGDNAMPTL3MBTL1 | |
| SCHEMBL6958634 | 0.77 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL16193026 | 0.77 | PLAU (0.59) | RAB9AHPGDHDAC1PLAUHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |