Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.69 |
| ▸ | NOS1 | P29475 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.53 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973673 | 0.84 | NOS1 (0.60) | NOS1NOS2NOS3 | |
| SCHEMBL6973670 | 0.84 | NOS1 (0.60) | NOS1NOS2NOS3 | |
| SCHEMBL6968104 | 0.83 | NOS1 (0.57) | NOS1NOS2HPGDNOS3 | |
| SCHEMBL6282503 | 0.81 | NOS1 (0.51) | NOS1NOS2HPGDNOS3 | |
| SCHEMBL6968445 | 0.81 | NOS1 (0.60) | NOS1TPSAB1NOS2HPGDNOS3 | |
| SCHEMBL6282506 | 0.81 | NOS1 (0.51) | NOS1NOS2HPGDNOS3 | |
| SCHEMBL6968123 | 0.81 | NOS1 (0.68) | NOS1NOS2NOS3 | |
| SCHEMBL6966986 | 0.80 | NOS1 (0.64) | NOS1PRSS1TPSAB1NOS2HPGD | |
| SCHEMBL9218996 | 0.79 | NOS1 (0.54) | NOS1NOS2NOS3 | |
| SCHEMBL9037862 | 0.77 | NPC1 (0.51) | PLAUHPGDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |