Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447175 | 0.87 | CYP1A2 (0.54) | CTSKCTSSCTSLCTSBLARS1 | |
| SCHEMBL9749394 | 0.87 | CYP1A2 (0.54) | CTSKCTSSCTSLCTSBLARS1 | |
| SCHEMBL9215213 | 0.87 | HRH4 (0.53) | CTSKHRH4CAPN1CAPN2MEN1 | |
| SCHEMBL11072087 | 0.86 | CTSK (0.60) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL7387364 | 0.86 | HRH4 (0.57) | HRH4MEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL5492509 | 0.85 | HRH4 (0.56) | HRH4MEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL5492506 | 0.85 | HRH4 (0.56) | HRH4MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL21342932 | 0.84 | KMT2A (0.57) | CTSKHRH4CAPN1CAPN2MEN1 | |
| SCHEMBL10414351 | 0.84 | SLC1A3 (0.57) | CTSKCAPN1CAPN2SLC1A3SLC1A1 | |
| SCHEMBL30392618 | 0.84 | HRH4 (0.50) | HRH4MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |