Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 5/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414351 | 0.95 | SLC1A3 (0.57) | CTSKSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL11061792 | 0.94 | TGM2 (0.56) | CTSKSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL11060790 | 0.94 | TGM2 (0.56) | CTSKSLC1A3SLC1A1LMNASMN1; SMN2 | |
| SCHEMBL9037992 | 0.86 | CTSK (0.50) | CTSKSLC1A3SLC1A1CTSSCTSL | |
| SCHEMBL10770391 | 0.85 | PSMB1 (0.52) | CTSKSLC1A3SLC1A1CTSSCTSL | |
| SCHEMBL10770383 | 0.85 | PSMB1 (0.52) | CTSKSLC1A3SLC1A1CTSSCTSL | |
| SCHEMBL27450496 | 0.85 | CTSK (0.57) | CTSKSLC1A3SLC1A1CTSSCTSL | |
| SCHEMBL8408312 | 0.85 | CTSK (0.61) | CTSKSLC1A3SLC1A1CTSSCTSL | |
| SCHEMBL6984142 | 0.85 | CTSK (0.57) | CTSKSLC1A3SLC1A1CTSSCTSL | |
| SCHEMBL27716946 | 0.85 | SLC1A3 (0.59) | CTSKSLC1A3SLC1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474800-A | PROTEASE INHIBITORS, MUSCULAR DYSTROPHY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-10-02 | — | — | US | disclosed |