Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 3/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18057080 | 0.89 | LPL (0.36) | IRAK4LPLLIPG | |
| SCHEMBL903402 | 0.89 | LPL (0.36) | IRAK4LPLLIPG | |
| SCHEMBL19318922 | 0.85 | LPL (0.36) | EGFRLPLLIPG | |
| SCHEMBL10215056 | 0.84 | SNCA (0.31) | — | |
| SCHEMBL10217790 | 0.82 | SNCA (0.33) | LPLLIPG | |
| SCHEMBL19226001 | 0.81 | LPL (0.31) | LPLLIPG | |
| SCHEMBL903693 | 0.80 | EGFR (0.32) | EGFRLPLLIPG | |
| SCHEMBL18061906 | 0.80 | ACLY (0.34) | EGFRLPLLIPG | |
| SCHEMBL15898090 | 0.79 | — | — | |
| SCHEMBL18957722 | 0.71 | MAOB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041014-A1 | TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |