Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432988 | 0.90 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL2632406 | 0.80 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL2439457 | 0.77 | MAPT (0.56) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL7094216 | 0.75 | EPHX2 (0.57) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL1278317 | 0.75 | EPHX2 (0.57) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL2438485 | 0.75 | EPHX2 (0.57) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27778609 | 0.75 | MAPT (0.54) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL28595923 | 0.75 | EPHX2 (0.57) | ALDH1A1MAPTL3MBTL1MAPK1CYP3A4 | |
| SCHEMBL1858152 | 0.74 | — | — | |
| SCHEMBL7287809 | 0.73 | L3MBTL1 (0.56) | MAPTL3MBTL1KDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747379-A1 | Derivatives of indole, indazole and benzisoxazole for the treatment of schizophrenia | ADIR ET COMPAGNIE (FR) | 1996-12-11 | — | — | EP | disclosed |