⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038543 | 1.00 | — | — | |
| SCHEMBL28503374 | 0.80 | ADRA2A (0.49) | — | |
| SCHEMBL6678356 | 0.79 | — | — | |
| SCHEMBL24922344 | 0.79 | — | — | |
| SCHEMBL3159038 | 0.77 | ADRA2A (0.61) | — | |
| SCHEMBL28824213 | 0.76 | — | — | |
| SCHEMBL5088326 | 0.75 | TAAR1 (0.50) | — | |
| SCHEMBL7878676 | 0.75 | TAAR1 (0.38) | — | |
| SCHEMBL14938536 | 0.73 | ALDH1A1 (0.48) | — | |
| SCHEMBL2742130 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341428-A | Production method of thiophene-2-ethylamine | 菏泽鸿特药业有限公司 | 2021-02-09 | — | — | CN | claimed |
| EP-0465358-B1 | 2-Thienylglycidic acid derivative, process for its preparation and its use as synthetic intermediate | SANOFI SA (FR) | 1996-02-07 | — | — | EP | claimed |
| US-5132435-A | From 2-theinylcarboxaldehyde and an isopropyl haloacetate; for making 2-thienlacetaldoxime and thieno 9(3,2-c)pyridine derivatives | SANOFI (FR) | 1992-07-21 | — | — | US | claimed |
| CN-117720433-A | Preparation method and application of oxime carbonate compound | 河南农业大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-112341428-A | Production method of thiophene-2-ethylamine | 菏泽鸿特药业有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112341428-A | Production method of thiophene-2-ethylamine | 菏泽鸿特药业有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-107522635-B | N-cyclopropyl nitrone derivatives and preparation method thereof | 东北师范大学 | 2020-02-14 | — | — | CN | disclosed |
| WO-2014031755-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | WO | disclosed |
| US-5132435-A | From 2-theinylcarboxaldehyde and an isopropyl haloacetate; for making 2-thienlacetaldoxime and thieno 9(3,2-c)pyridine derivatives | SANOFI (FR) | 1992-07-21 | — | — | US | disclosed |
| US-5132435-A | From 2-theinylcarboxaldehyde and an isopropyl haloacetate; for making 2-thienlacetaldoxime and thieno 9(3,2-c)pyridine derivatives | SANOFI (FR) | 1992-07-21 | — | — | US | disclosed |
| EP-0465358-A1 | 2-Thienylglycidic acid derivative, process for its preparation and its use as synthetic intermediate | SANOFI (FR) | 1992-01-08 | — | — | EP | disclosed |