Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 4/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038247 | 0.86 | HTT (0.39) | HTTCACNA1GCACNA1HCNR2CACNA1I | |
| SCHEMBL9036510 | 0.86 | GALR3 (0.40) | HTTCACNA1GCACNA1HCNR2CACNA1I | |
| SCHEMBL9038157 | 0.85 | GALR3 (0.50) | HTTCNR2AURKARPS6KB1MEN1 | |
| SCHEMBL9039253 | 0.85 | GALR3 (0.40) | HTTCACNA1GCACNA1HCNR2CACNA1I | |
| SCHEMBL9037904 | 0.81 | GALR3 (0.46) | HTTCNR2AURKARPS6KB1RAB9A | |
| SCHEMBL5705471 | 0.78 | VNN1 (0.40) | HTTAURKARPS6KB1ACACBTP53 | |
| Flufenerim SCHEMBL29429245 | 0.74 | CYP3A4 (0.42) | HTTCNR2MEN1KMT2ARAB9A | |
| Flufenerim SCHEMBL26581 | 0.74 | CYP3A4 (0.42) | HTTCNR2MEN1KMT2ARAB9A | |
| SCHEMBL15684743 | 0.74 | PDE2A (0.41) | HTTKCNH2AURKAMEN1KMT2A | |
| SCHEMBL15684873 | 0.73 | PDE2A (0.41) | HTTKCNH2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665225-B1 | 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same | UBE INDUSTRIES (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5498612-A | INSECTICIDE, ACARICIDE, FUNGICIDE, NEMATOCIDE | UBE INDUSTRIES, LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0665225-A1 | 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |