Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14738746 | 0.84 | DPP4 (0.40) | DPP4DPP8DPP9DPP7KCNH2 | |
| SCHEMBL14738064 | 0.84 | DPP4 (0.40) | DPP4DPP8DPP9DPP7KCNH2 | |
| SCHEMBL23103231 | 0.79 | PIK3CD (0.47) | DPP4DPP8DPP9KDM4E | |
| SCHEMBL12041121 | 0.79 | PIK3CD (0.47) | DPP4DPP8DPP9KDM4E | |
| SCHEMBL23103243 | 0.79 | PIK3CD (0.47) | DPP4DPP8DPP9KDM4E | |
| SCHEMBL19982023 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL19981827 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL24616000 | 0.76 | SLC6A3 (0.37) | DPP4DPP8DPP9SLC6A3KDM4E | |
| SCHEMBL24616051 | 0.76 | SLC6A3 (0.37) | DPP4DPP8DPP9SLC6A3KDM4E | |
| SCHEMBL21613633 | 0.76 | DPP4 (0.33) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041014-A1 | TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |