Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.52 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9038823 | 0.82 | S1PR5 (0.67) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL15367665 | 0.81 | S1PR5 (0.59) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL1717074 | 0.80 | LTA4H (0.63) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL8263431 | 0.80 | LTA4H (0.63) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL28943257 | 0.80 | SCN4A (0.55) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL24131137 | 0.79 | L3MBTL1 (0.60) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL24131658 | 0.79 | L3MBTL1 (0.60) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL8601138 | 0.78 | S1PR5 (0.61) | S1PR5SCN4AMEN1TSHRKMT2A | |
| SCHEMBL1545229 | 0.78 | L3MBTL1 (0.74) | ATML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL14022760 | 0.78 | L3MBTL1 (0.74) | ATML3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |