Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033990 | 0.89 | GPR84 (0.45) | IDO1CYP19A1CYP11B1CYP11B2GPR84 | |
| SCHEMBL3321623 | 0.86 | IDO1 (0.54) | TAAR1IDO1MAOBTHRATHRB | |
| SCHEMBL9034118 | 0.84 | GPR84 (0.39) | TAAR1SIRT2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2452382 | 0.78 | NPC1 (0.46) | IDO1MAOBCYP11B1CYP11B2FFAR1 | |
| SCHEMBL5543228 | 0.77 | TAAR1 (0.51) | TAAR1IDO1SIRT2MIFMAOB | |
| SCHEMBL4427337 | 0.77 | IDO1 (0.46) | IDO1MAOB | |
| SCHEMBL5153857 | 0.75 | CHRM2 (0.45) | FFAR1 | |
| SCHEMBL2449678 | 0.74 | CYP11B1 (0.40) | TAAR1SIRT2MAOBCYP11B1CYP11B2 | |
| SCHEMBL14647919 | 0.73 | PPARG (0.40) | SCN8AGPR84DAOFFAR1FFAR4 | |
| SCHEMBL10840243 | 0.73 | TSHR (0.47) | MAOBCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748320-A1 | PRODRUGS OF MORPHOLINE TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-12-18 | — | — | EP | disclosed |
| US-4578107-A | Herbicidal imidazolidine-2-one derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-03-25 | — | — | US | disclosed |