Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245398 | 0.86 | MAOB (0.51) | TSHRHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL13812981 | 0.79 | MEN1 (0.55) | TSHRSIGMAR1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10840250 | 0.78 | TSHR (0.49) | TSHRSIGMAR1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL2452382 | 0.76 | NPC1 (0.46) | CYP11B1CYP11B2ALDH1A1MAOAMAOB | |
| SCHEMBL10956755 | 0.76 | SIGMAR1 (0.54) | TSHRSIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6674437 | 0.75 | TSHR (0.59) | TSHRSIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18165912 | 0.74 | TSHR (0.57) | TSHRSIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1520674 | 0.74 | TSHR (0.57) | TSHRSIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10840699 | 0.73 | ALDH1A1 (0.48) | TSHRMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL7867611 | 0.73 | IDO1 (0.50) | HTR1AADRA1DADRA1AADRA1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4578107-A | Herbicidal imidazolidine-2-one derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1986-03-25 | — | — | US | disclosed |