Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | PTAFR | P25105 | 9/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228131 | 0.90 | MEN1 (0.47) | BRD4OPRK1PTAFRPDE4D | |
| SCHEMBL2539664 | 0.90 | BRD4 (0.54) | BRD4GABRA1GABRA5GABRA2GABRB2 | |
| SCHEMBL2538078 | 0.88 | BRD4 (0.44) | BRD4PTAFR | |
| SCHEMBL21320337 | 0.88 | BRD4 (0.47) | BRD4OPRK1PTAFRPDE4D | |
| SCHEMBL2537139 | 0.88 | BRD4 (0.56) | BRD4GABRA1GABRA5GABRA2GABRB2 | |
| SCHEMBL2538162 | 0.88 | BRD4 (0.45) | BRD4OPRK1PTAFRPDE4D | |
| SCHEMBL2541879 | 0.87 | BRD4 (0.42) | BRD4OPRK1PTAFRPDE4D | |
| SCHEMBL2542927 | 0.87 | CYP11B2 (0.44) | BRD4GABRA1GABRA5GABRA2GABRB2 | |
| SCHEMBL23745163 | 0.86 | OPRK1 (0.45) | BRD4OPRK1PTAFRPDE4D | |
| SCHEMBL2541825 | 0.86 | BRD4 (0.42) | BRD4GABRA1GABRA5GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087096-A1 | P53 MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-06 | — | — | WO | disclosed |
| EP-0692483-A1 | CELL ADHESION INHIBITOR AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-01-17 | — | — | EP | disclosed |