Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039009 | 1.00 | TGM2 (0.48) | TGM2ABL1RETPDGFRBFGFR1 | |
| SCHEMBL249816 | 0.83 | ALDH1A1 (0.64) | TGM2ABL1RETPDGFRBFGFR1 | |
| SCHEMBL249817 | 0.83 | ALDH1A1 (0.64) | TGM2ABL1RETPDGFRBFGFR1 | |
| SCHEMBL14524539 | 0.83 | ALDH1A1 (0.64) | TGM2ABL1RETPDGFRBFGFR1 | |
| SCHEMBL9041488 | 0.82 | TGM2 (0.55) | TGM2ALKIDO1MAPTALDH1A1 | |
| SCHEMBL9041481 | 0.82 | TGM2 (0.55) | TGM2ALKIDO1MAPTALDH1A1 | |
| SCHEMBL9041602 | 0.77 | TGM2 (0.55) | TGM2IDO1MAPTALDH1A1HTT | |
| SCHEMBL9041594 | 0.77 | TGM2 (0.55) | TGM2IDO1MAPTALDH1A1HTT | |
| SCHEMBL9041507 | 0.73 | TGM2 (0.46) | TGM2RETPDGFRBFGFR1FLT3 | |
| SCHEMBL9041503 | 0.73 | TGM2 (0.46) | TGM2RETPDGFRBFGFR1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347831-B1 | Pyridine derivatives and intermediates thereof | KYOWA HAKKO KOGYO KK (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-4971964-A | INHIBITORS OF THROMBOXANE SYNTHASE, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORU AGENTS, CANCER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |