Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12523709 | 0.78 | NPC1 (0.39) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL903913 | 0.73 | OGA (0.36) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL26790070 | 0.71 | GPR119 (0.39) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL2597089 | 0.70 | OGA (0.42) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL22737894 | 0.70 | ALDH1A1 (0.61) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL22737504 | 0.70 | HSD17B10 (0.43) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL12503186 | 0.70 | OGA (0.47) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL12525139 | 0.70 | OGA (0.47) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL10068057 | 0.69 | NPC1 (0.40) | KDM4ENPC1RAB9AGPR119OGA | |
| SCHEMBL20064433 | 0.69 | HRH3 (0.41) | KDM4ENPC1RAB9AGPR119OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |