SCHEMBL903924

SCHEMBL903924

CC(C)(C)OC(=O)N1CC2[C@H](COc3ccc(-c4ccc(S(C)(=O)=O)cn4)cc3)[C@@]2(C)C1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067583 0.83 GPR119 (0.59) GPR119
SCHEMBL10067768 0.83 GPR119 (0.47) GPR119
SCHEMBL387275 0.81 GPR119 (0.66) GPR119
SCHEMBL387392 0.76 GPR119 (0.69) GPR119
SCHEMBL10068006 0.74 GPR119 (0.45) GPR119
SCHEMBL29812869 0.74 GPR119 (0.56) GPR119
SCHEMBL29812900 0.74 GPR119 (0.56) GPR119
SCHEMBL26966761 0.74 GPR119 (0.56) GPR119
SCHEMBL904068 0.73 GPR119 (0.46) GPR119
SCHEMBL10067566 0.72 GPR119 (0.57) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012041158-A1 TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF 上海恒瑞医药有限公司 (CN) 2012-04-05 WO disclosed