Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RORB | Q92753 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042068 | 0.84 | LMNA (0.49) | LMNAALOX15HSD17B10GAAHTT | |
| SCHEMBL9525622 | 0.84 | ALOX15 (0.50) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL9522372 | 0.84 | ALOX15 (0.50) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL10464665 | 0.84 | ALOX15 (0.50) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL9522274 | 0.84 | ALOX15 (0.50) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL9522929 | 0.84 | ALOX15 (0.50) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL9042031 | 0.83 | LMNA (0.54) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL9669246 | 0.82 | LMNA (0.47) | LMNAALOX15HSD17B10GAAMAPT | |
| SCHEMBL8689517 | 0.82 | LMNA (0.47) | LMNAALOX15HSD17B10GAAMAPK1 | |
| SCHEMBL9042453 | 0.82 | LMNA (0.47) | LMNAALOX15HSD17B10GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61134388-A | — | — | None | — | — | JP | disclosed |
| CN-101648939-B | Method for synthesizing 2-glycyl amine-3-ortho-chlorobenzene formyl-5-ethylthiophene | SHANGHAI OLI BIOTECH CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101648939-A | Method for synthesizing 2-glycyl amine-3-ortho-chlorobenzene formyl-5-ethylthiophene | SHANGHAI OLI BIOTECH CO LTD | 2010-02-17 | — | — | CN | disclosed |
| EP-0472116-B1 | Thienopyridine Derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5256782-A | For anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5143919-A | Acyl-CoA:cholesterol acyltransferase inhibitors; anticholesterol agents; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0472116-A1 | Thienopyridine Derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |
| JP-S61134388-A | 2-SUBSTITUTED AMINOACETAMIDO-3-(O-CHLOROBENZOYL)-5-ETHYL-THIOPHENE DERIVATIVE AND PRODUCTION THEREOF | NIPPON IYAKUHIN KOGYO KK | 1986-06-21 | — | — | JP | disclosed |
| US-4017620-A | MUSCLE RELAXANTS, ANTICONVULSANTS, SEDATIVES, TRANQUILIZERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-04-12 | — | — | US | disclosed |
| US-3957783-A | URICOSURIC ACTIVITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-05-18 | — | — | US | disclosed |