Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199293 | 0.81 | HTR2B (0.43) | KDM4EALDH1A1MAPK1BLMNPSR1 | |
| SCHEMBL7377250 | 0.77 | CREB1 (0.34) | CYP1A2CYP3A4CYP2C19CNR2PPARG | |
| SCHEMBL7374423 | 0.76 | NQO1 (0.36) | CYP2C9 | |
| SCHEMBL7374524 | 0.76 | MAOB (0.42) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL7373680 | 0.75 | RXRA (0.34) | KDM4EALDH1A1MAPK1FFAR1PPARG | |
| SCHEMBL9196600 | 0.73 | HTR2B (0.46) | KDM4EALDH1A1MAPK1BLMNPSR1 | |
| SCHEMBL6175609 | 0.73 | CYP2C9 (0.54) | KDM4EALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL6173602 | 0.73 | CYP2C9 (0.54) | KDM4EALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL6174912 | 0.73 | CYP2C9 (0.54) | KDM4EALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL6175124 | 0.73 | CYP2C9 (0.54) | KDM4EALDH1A1CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729466-A1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014014-A2 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |