Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040888 | 0.86 | DHFR (0.39) | — | |
| SCHEMBL9040897 | 0.86 | DHFR (0.39) | — | |
| SCHEMBL9040851 | 0.82 | NAMPT (0.35) | NAMPT | |
| SCHEMBL9043807 | 0.81 | TYMS (0.44) | NAMPT | |
| SCHEMBL9043796 | 0.81 | TYMS (0.44) | NAMPT | |
| SCHEMBL9042923 | 0.75 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL9439883 | 0.75 | FOLR1 (0.44) | NAMPT | |
| SCHEMBL9041997 | 0.72 | HDAC3 (0.43) | HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL9040305 | 0.72 | NAMPT (0.42) | NAMPT | |
| SCHEMBL9039103 | 0.71 | DHFR (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400562-B1 | Pyrrolopyrimidines, their production and use as tumoricidal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-08-21 | — | — | EP | disclosed |