Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLR1 | P15328 | 4/20 | 0.44 |
| ▸ | SLC19A1 | P41440 | 4/20 | 0.44 |
| ▸ | SLC46A1 | Q96NT5 | 4/20 | 0.44 |
| ▸ | GART | P22102 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439860 | 0.85 | FOLR1 (0.51) | FOLR1SLC19A1SLC46A1GARTNAMPT | |
| SCHEMBL9859911 | 0.82 | FOLR1 (0.36) | FOLR1SLC19A1SLC46A1 | |
| Trifluoroacetic Acid SCHEMBL9555051 | 0.82 | FOLR1 (0.47) | FOLR1SLC19A1SLC46A1GARTNAMPT | |
| SCHEMBL8997147 | 0.81 | NAMPT (0.50) | NAMPT | |
| SCHEMBL9564187 | 0.80 | FOLR1 (0.34) | FOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9439960 | 0.76 | FOLR1 (0.57) | FOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9439954 | 0.76 | FOLR1 (0.57) | FOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9439728 | 0.75 | FOLR1 (0.76) | FOLR1SLC19A1SLC46A1GART | |
| SCHEMBL9039846 | 0.75 | NAMPT (0.34) | NAMPT | |
| SCHEMBL17813067 | 0.74 | FOLR1 (0.65) | FOLR1SLC19A1SLC46A1GART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354754-A | Antitumor and -carcinogenic agents; treating human epidermoid carcinoma KB | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |