SCHEMBL9040271

SCHEMBL9040271

CCCCc1nc2cccc(O)c2n1Cc1ccc(-c2ccccc2OC(=O)OC(C)(C)C)cc1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 2/20 0.52
AGTR1 P30556 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9039227 0.92 AGTR2 (0.52) AGTR2AGTR1
SCHEMBL9043130 0.91 AGTR1 (0.51) AGTR2AGTR1
SCHEMBL9041454 0.90 PPARG (0.52) AGTR2AGTR1
SCHEMBL9043313 0.89 AGTR2 (0.56) AGTR2AGTR1
SCHEMBL9041236 0.89 AGTR1 (0.66) AGTR2AGTR1
SCHEMBL9040250 0.89 AGTR2 (0.51) AGTR2AGTR1
SCHEMBL9043963 0.87 AGTR1 (0.51) AGTR2AGTR1
SCHEMBL9044918 0.87 PPARG (0.46) AGTR2AGTR1
SCHEMBL9704755 0.87 AGTR2 (0.49) AGTR2AGTR1
SCHEMBL8944824 0.86 AGTR2 (0.58) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0392317-B1 Benzimidazoles, drugs containing these compounds and process for their preparation THOMAE GMBH DR K (DE) 1996-01-03 EP disclosed