⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874921 | 0.83 | — | — | |
| Suronacrine SCHEMBL975421 | 0.81 | — | — | |
| SCHEMBL9874125 | 0.81 | — | — | |
| SCHEMBL9876011 | 0.80 | — | — | |
| SCHEMBL9875693 | 0.78 | CYP1A2 (0.65) | — | |
| SCHEMBL9875581 | 0.78 | PABPC1 (0.65) | — | |
| SCHEMBL9875398 | 0.78 | — | — | |
| SCHEMBL9876171 | 0.77 | — | — | |
| SCHEMBL9875846 | 0.77 | — | — | |
| SCHEMBL9876020 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112829-A | Intermediates for Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | claimed |
| EP-0430114-B1 | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds, a process and intermediates for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5112829-A | Intermediates for Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0430114-A2 | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-05 | — | — | EP | disclosed |
| US-4994452-A | Memory disfunction | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-02-19 | — | — | US | disclosed |