SCHEMBL9875693

SCHEMBL9875693

CNc1c2c(nc3ccccc13)CCCC2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.65
CYP2C9 P11712 1/20 0.65
TSHR P16473 1/20 0.65
ALDH1A1 P00352 1/20 0.65
NR3C1 P04150 1/20 0.65
ACHE P22303 1/20 0.65
KCNH2 Q12809 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9749136 0.84 CYP1A2 (0.51) CYP1A2CYP2C9TSHRALDH1A1NR3C1
SCHEMBL9874125 0.84
SCHEMBL10846908 0.83 ACHE (0.51) CYP1A2CYP2C9TSHRALDH1A1NR3C1
SCHEMBL10847217 0.82 CYP1A2 (0.47) CYP1A2CYP2C9TSHRALDH1A1NR3C1
Suronacrine SCHEMBL975421 0.82
SCHEMBL10847762 0.82
SCHEMBL9875581 0.81 PABPC1 (0.65)
SCHEMBL10843860 0.80 BCHE (0.50) ACHE
SCHEMBL9876011 0.80
SCHEMBL9876020 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4631286-A MEMORY ENHANCERS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1986-12-23 US claimed
EP-2681554-B1 BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR BECTON DICKINSON CO (US) 2017-08-09 EP disclosed
US-9459187-B2 Blood collection device containing lysophospholipase inhibitor BECTON, DICKINSON AND COMPANY (US) 2016-10-04 US disclosed
CN-103477224-B Blood collection device containing lysophospholipase inhibitor BECTON, DICKINSON AND CO. (US) 2015-12-23 CN disclosed
CN-104244902-A Sample collection devices with blood stabilizing agents BECTON DICKINSON CO 2014-12-24 CN disclosed
US-20140030754-A1 BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR BECTON, DICKINSON AND COMPANY (US) 2014-01-30 US disclosed
CN-103477224-A Blood collection device containing lysophospholipase inhibitor BECTON DICKINSON CO 2013-12-25 CN disclosed
CN-203203992-U Blood collection device containing lysophospholipase inhibitor BECTON DICKINSON CO 2013-09-18 CN disclosed
US-20130209985-A1 SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS BECTON, DICKINSON AND COMPANY 2013-08-15 US disclosed
EP-0179383-B1 9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1-OL AND RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-05-29 EP disclosed
US-4839364-A ALZHEIMER*S DISEASE; CHOLINESTERASE INHIBITORS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1989-06-13 US disclosed
US-4835275-A Method of preparing 9-amino-1,2,3,4,-tetrahydroacridin-1-ones and related compounds HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1989-05-30 US disclosed
US-4754050-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-06-28 US disclosed
US-4695573-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1987-09-22 US disclosed
US-4631286-A MEMORY ENHANCERS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1986-12-23 US disclosed
EP-0179383-A2 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1986-04-30 EP disclosed