Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055714 | 0.77 | OPRM1 (0.44) | SMN1; SMN2HPGDLMNAKMT2AMEN1 | |
| SCHEMBL6140943 | 0.77 | OPRM1 (0.44) | SMN1; SMN2HPGDLMNAKMT2AMEN1 | |
| SCHEMBL5673263 | 0.77 | OPRM1 (0.44) | SMN1; SMN2HPGDLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5444914 | 0.76 | OPRM1 (0.43) | SMN1; SMN2HPGDLMNAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL4846461 | 0.76 | OPRM1 (0.43) | SMN1; SMN2HPGDLMNAMAPTNPSR1 | |
| SCHEMBL8840349 | 0.73 | ALOX5 (0.45) | KEAP1HPGDLMNAKMT2AMEN1 | |
| SCHEMBL10441844 | 0.73 | HPGD (0.64) | SMN1; SMN2NPC1RAB9AHPGDLMNA | |
| SCHEMBL8947244 | 0.71 | ALOX5 (0.50) | KEAP1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10484390 | 0.69 | ALOX5 (0.43) | KEAP1HPGDKMT2AMEN1MAPT | |
| SCHEMBL6630179 | 0.68 | ALOX5 (0.42) | SMN1; SMN2HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466569-B1 | Process for preparation of N-phenylacetyl derivative of tetrahydrothieno[3,2-c]pyridine and intermediate of synthesis | SANOFI SA (FR) | 1996-04-17 | — | — | EP | claimed |
| EP-0466569-A1 | Process for preparation of N-phenylacetyl derivative of tetrahydrothieno[3,2-c]pyridine and intermediate of synthesis | SANOFI (FR) | 1992-01-15 | — | — | EP | claimed |
| EP-0466569-B1 | Process for preparation of N-phenylacetyl derivative of tetrahydrothieno[3,2-c]pyridine and intermediate of synthesis | SANOFI SA (FR) | 1996-04-17 | — | — | EP | disclosed |
| EP-0466569-A1 | Process for preparation of N-phenylacetyl derivative of tetrahydrothieno[3,2-c]pyridine and intermediate of synthesis | SANOFI (FR) | 1992-01-15 | — | — | EP | disclosed |