Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 18/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040304 | 1.00 | ABCB1 (0.39) | ABCB1ABCC9KDM4E | |
| SCHEMBL481900 | 0.81 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL4023253 | 0.81 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9363607 | 0.81 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL6273195 | 0.81 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL482249 | 0.81 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 0.81 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL5868353 | 0.74 | IDO1 (0.40) | ABCB1 | |
| SCHEMBL6274078 | 0.74 | IDO1 (0.40) | ABCB1 | |
| SCHEMBL5868357 | 0.74 | IDO1 (0.40) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401010-B1 | Pyranyl cyanoguanidine derivatives | SQUIBB & SONS INC (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5140031-A | Pyranyl cyanoguanidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0401010-A2 | Pyranyl cyanoguanidine derivatives | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | disclosed |