Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273195 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL482249 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL4023253 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9363607 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| Hydrazinecarboxamide SCHEMBL9398507 | 0.87 | ABCC9 (0.50) | ABCB1KDM4E | |
| SCHEMBL9767316 | 0.83 | ABCB1 (0.46) | ABCB1KDM4E | |
| SCHEMBL9040308 | 0.81 | ABCB1 (0.39) | ABCB1KDM4E | |
| SCHEMBL9040304 | 0.81 | ABCB1 (0.39) | ABCB1KDM4E | |
| SCHEMBL9765458 | 0.81 | ABCB1 (0.43) | ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409651-B1 | New Process for the preparation of anti-hypertensive benzopyran derivative | ALKALOIDA VEGYESZETI GYAR (HU) | 1995-05-03 | — | — | EP | claimed |
| EP-0430621-A2 | Process for the preparation of chiral 3,4-epoxy benzopyrans | Beecham Group p.l.c. (GB) | 1991-06-05 | — | — | EP | claimed |
| EP-0409651-A1 | New Process for the preparation of anti-hypertensive benzopyran derivative | ALKALOIDA VEGYESZETI GYAR (HU) | 1991-01-23 | — | — | EP | claimed |
| US-4758677-A | Cyanobenzano [b] pyrans | BEECHAM GROUP P.L.C (GB) | 1988-07-19 | — | — | US | claimed |
| JP-3058988-A | — | — | None | — | — | JP | disclosed |
| JP-3190878-A | — | — | None | — | — | JP | disclosed |
| JP-4261172-A | — | — | None | — | — | JP | disclosed |
| EP-1937669-B9 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA NV (BE) | 2012-07-18 | — | — | EP | disclosed |
| EP-1937669-B1 | NOVEL BENZOPYRAN DERIVATIVES AS POTASSIUM CHANNEL OPENERS | JANSSEN PHARMACEUTICA NV (BE) | 2012-02-01 | — | — | EP | disclosed |
| US-7838553-B2 | Benzopyran derivatives as potassium channel openers | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-23 | — | — | US | disclosed |
| US-7812183-B2 | Benzopyran derivatives as potassium channel openers | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-12 | — | — | US | disclosed |
| EP-1940516-A2 | BENZOPYRAN AND PYRANOPYRIDINE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | Janssen Pharmaceutica, N.V. (BE) | 2008-07-09 | — | — | EP | disclosed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |
| EP-0093535-A1 | Novel chromenes and chromans | BEECHAM GROUP PLC (GB) | 1983-11-09 | — | — | EP | disclosed |
| US-4391815-A | VASODILATION, HYPOTENSIVE | BEECHAM GROUP LIMITED (GB) | 1983-07-05 | — | — | US | disclosed |
| EP-0009912-B1 | CHROMANOL DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | BEECHAM GROUP PLC (GB) | 1983-06-22 | — | — | EP | disclosed |
| EP-0076075-A1 | Pharmaceutically active benzopyran compounds | BEECHAM GROUP PLC (GB) | 1983-04-06 | — | — | EP | disclosed |
| EP-0046652-A1 | Chromanol derivatives, their production and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1982-03-03 | — | — | EP | disclosed |
| US-4251537-A | Hypotensive 3,4-dihydro-2,2-dimethyl-4-amino-2H-benzo[b]pyran-3-ols | BEECHAM GROUP LIMITED (GB) | 1981-02-17 | — | — | US | disclosed |
| EP-0009912-A1 | Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them | BEECHAM GROUP PLC (GB) | 1980-04-16 | — | — | EP | disclosed |