Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273195 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL482249 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9363607 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL481900 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| SCHEMBL9371324 | 1.00 | ABCB1 (0.56) | ABCB1KDM4E | |
| Hydrazinecarboxamide SCHEMBL9398507 | 0.87 | ABCC9 (0.50) | ABCB1KDM4E | |
| SCHEMBL9767316 | 0.83 | ABCB1 (0.46) | ABCB1KDM4E | |
| SCHEMBL9040308 | 0.81 | ABCB1 (0.39) | ABCB1KDM4E | |
| SCHEMBL9040304 | 0.81 | ABCB1 (0.39) | ABCB1KDM4E | |
| SCHEMBL9765458 | 0.81 | ABCB1 (0.43) | ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430621-A2 | Process for the preparation of chiral 3,4-epoxy benzopyrans | Beecham Group p.l.c. (GB) | 1991-06-05 | — | — | EP | claimed |
| EP-1499610-B1 | BENZOPYRAN DERIVATIVES SUBSTITUTED WITH SECONDARY AMINES INCLUDING TETRAZOLE, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HITEK CO LTD (KR) | 2009-01-21 | — | — | EP | disclosed |
| US-7414068-B2 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2008-08-19 | — | — | US | disclosed |
| US-7041700-B2 | Substituted benzopyran derivatives against arrhythmia | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20060035948-A1 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2006-02-16 | — | — | US | disclosed |
| US-20040152763-A1 | Substituted benzopyran derivatives against arrhythmia | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-5629429-A | Process for preparing 4-arylamino-benzopyran and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| US-5453421-A | Aryl and heterocyclic substituted propenamide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0648758-A1 | 4-Arylamino-benzopyran and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5393771-A | 4-substituted benzopyran and related compounds | BRISOL-MYERS SQUIBB COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5374643-A | Aryl urea (thiourea) and cyanoguanidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1994-12-20 | — | — | US | disclosed |
| EP-0624581-A2 | 4-Substituted benzopyran and related compounds useful as pharmaceutical agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-11-17 | — | — | EP | disclosed |
| EP-0587188-A2 | Aryl and heterocyclic substituted propenamide derivatives | E.R. SQUIBB & SONS, INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0587180-A2 | Aryl urea (Thiourea) and cyanoguanidine derivatives | E.R. SQUIBB & SONS, INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1993004182-A1 | PROCESS FOR THE PREPARATION OF 3,4-EPOXY BENZOPYRANS AND PYRANOPYRIDINES BY A MICROBIAL EPOXIDASE | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035948-A1 | Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them | TH, TNNI3, NOS3 | ABCB1 1370/4885KDM4E 936/4885 |
| US-20040152763-A1 | Substituted benzopyran derivatives against arrhythmia | CBR1, KCNH1, SCN8A | ABCB1 214/4885KDM4E 3555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.