Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15153618 | 0.92 | MAPT (0.47) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7337554 | 0.88 | MAPT (0.44) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7659602 | 0.83 | TDP1 (0.56) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11655565 | 0.83 | TDP1 (0.56) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2207325 | 0.82 | L3MBTL1 (0.48) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1300124 | 0.81 | MAPT (0.47) | MAPTKMT2ATSHRALDH1A1POLB | |
| SCHEMBL6901399 | 0.81 | TDP1 (0.55) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21073906 | 0.81 | TDP1 (0.55) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4302618 | 0.80 | MAPT (0.42) | MAPTTDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL455720 | 0.79 | TDP1 (0.53) | MAPTTDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328924-B1 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-4937240-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-06-26 | — | — | US | disclosed |
| EP-0328924-A2 | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-08-23 | — | — | EP | disclosed |