Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067595 | 0.94 | L3MBTL1 (0.47) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL9453302 | 0.93 | MAPT (0.49) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL7074449 | 0.93 | MAPT (0.49) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL8342328 | 0.93 | TDP1 (0.44) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL7224713 | 0.93 | MAPT (0.49) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| Malonic Acid SCHEMBL6827749 | 0.92 | TDP1 (0.44) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL2203256 | 0.88 | L3MBTL1 (0.43) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| Butane SCHEMBL6824986 | 0.85 | L3MBTL1 (0.42) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL15445274 | 0.83 | ALDH1A1 (0.47) | L3MBTL1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL13347919 | 0.83 | ALDH1A1 (0.40) | L3MBTL1MAPK1TDP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110842393-B | Low-temperature lead-free soldering paste and preparation method thereof | 苏州优诺电子材料科技有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-110842393-A | Low-temperature lead-free soldering paste and preparation method thereof | 苏州优诺电子材料科技有限公司 | 2020-02-28 | — | — | CN | claimed |
| EP-3538526-B1 | CYCLOBUTANE- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-05-02 | — | — | US | disclosed |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-05-02 | — | — | US | disclosed |
| CN-110167934-B | Cyclobutane-and azetidine-containing monocyclic and spiro compounds as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-110842393-B | Low-temperature lead-free soldering paste and preparation method thereof | 苏州优诺电子材料科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-20210246136-A1 | CYCLOBUTANES- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-08-12 | — | — | US | disclosed |
| US-11014922-B2 | Cyclobutane- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-25 | — | — | US | disclosed |
| CN-110842393-A | Low-temperature lead-free soldering paste and preparation method thereof | 苏州优诺电子材料科技有限公司 | 2020-02-28 | — | — | CN | disclosed |
| EP-3538526-A1 | CYCLOBUTANE- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | Bristol-Myers Squibb Company (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2004043367-A2 | FUSED HETEROCYCLIC COMPOUNDS AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |
| EP-0430065-B1 | Barbiturate assay compositions and methods | ABBOTT LAB (US) | 1995-11-15 | — | — | EP | disclosed |
| US-5241036-A | Ion selective electrodes | NATIONAL SCIENCE COUNCIL (TW) | 1993-08-31 | — | — | US | disclosed |
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-5099020-A | Immunoassay with fluorescent compounds | ABBOTT LABORATORIES (US) | 1992-03-24 | — | — | US | disclosed |
| US-5096838-A | Fluorescent tracers for detection of barbiturates and for antiserums | ABBOTT LABORATORIES (US) | 1992-03-17 | — | — | US | disclosed |
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0430065-A2 | Barbiturate assay compositions and methods | ABBOTT LABORATORIES (US) | 1991-06-05 | — | — | EP | disclosed |
| EP-0405391-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246136-A1 | CYCLOBUTANES- AND AZETIDINE-CONTAINING MONO AND SPIROCYCLIC COMPOUNDS AS ALPHA V INTEGRIN INHIBITORS | ITGB1, ITGAV, ITGA1 | L3MBTL1 4419/4885MAPK1 1800/4885TDP1 4566/4885 |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | ITGB1, ITGB2, ITGA1 | L3MBTL1 4326/4885MAPK1 1812/4885TDP1 4658/4885 |
| US-11014922-B2 | Cyclobutane- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | ITGB1, ITGB2, ITGA1 | L3MBTL1 4426/4885MAPK1 1740/4885TDP1 4624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.