⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042519 | 0.85 | AR (0.32) | — | |
| SCHEMBL9043482 | 0.78 | CYP11B1 (0.30) | — | |
| SCHEMBL9041344 | 0.75 | AR (0.33) | — | |
| SCHEMBL9043191 | 0.75 | LMNA (0.36) | — | |
| SCHEMBL9043089 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL9042036 | 0.70 | TRPA1 (0.34) | — | |
| SCHEMBL305883 | 0.68 | MAOB (0.42) | — | |
| SCHEMBL15716128 | 0.64 | MAOB (0.39) | — | |
| SCHEMBL9041668 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL9043471 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-B1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |