Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044926 | 0.81 | PKM (0.60) | ALDH1A1CYP1A2L3MBTL1ATMPOLB | |
| SCHEMBL9045029 | 0.79 | CYP1A2 (0.78) | ALDH1A1CYP1A2L3MBTL1ATMPOLB | |
| SCHEMBL27354255 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP1A2L3MBTL1ATMPOLB | |
| SCHEMBL13907450 | 0.78 | MAPT (0.49) | ALDH1A1CYP1A2POLBMAPTSMN1; SMN2 | |
| SCHEMBL6052462 | 0.76 | ATM (0.69) | ALDH1A1CYP1A2L3MBTL1ATMPOLB | |
| SCHEMBL3211700 | 0.76 | ATM (0.69) | ALDH1A1CYP1A2L3MBTL1ATMPOLB | |
| SCHEMBL28502778 | 0.76 | ATM (0.62) | ALDH1A1CYP1A2L3MBTL1ATMPOLB | |
| SCHEMBL92865 | 0.76 | NPC1 (0.54) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9041022 | 0.72 | NPC1 (0.41) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9043748 | 0.71 | TP53 (0.35) | ALDH1A1CYP1A2MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-B1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5215994-A | Treating or preventing hypertension or heart failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5210092-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |