Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039302 | 0.89 | PKM (0.67) | PKMFGFR1L3MBTL1MAPTLMNA | |
| SCHEMBL19911383 | 0.88 | LMNA (0.54) | PKMFGFR1L3MBTL1MAPTLMNA | |
| SCHEMBL19911394 | 0.87 | FGFR1 (0.56) | PKMFGFR1L3MBTL1MAPTLMNA | |
| SCHEMBL7353128 | 0.85 | PKM (0.65) | PKMFGFR1L3MBTL1MAPTLMNA | |
| SCHEMBL7030954 | 0.84 | PKM (0.54) | PKMFGFR1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL19911402 | 0.84 | PKM (0.54) | PKMFGFR1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL19911390 | 0.81 | FGFR1 (0.56) | PKMFGFR1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL2847738 | 0.80 | PKM (0.81) | PKMFGFR1ALDH1A1HTT | |
| SCHEMBL4918973 | 0.80 | PKM (0.50) | PKMFGFR1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL7029418 | 0.80 | PKM (0.62) | PKMFGFR1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-B1 | Hexitol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5053408-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |