Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414539 | 0.91 | KMT2A (0.56) | KMT2AMEN1NCOA1NCOA3CYP3A4 | |
| SCHEMBL366012 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1CYP3A4POLBMAPT | |
| SCHEMBL1012937 | 0.81 | BAZ1A (0.60) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| SCHEMBL30626616 | 0.81 | BAZ1A (0.60) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| SCHEMBL9040036 | 0.81 | PDE4D (0.56) | KMT2AMEN1POLBMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL27777765 | 0.80 | ALDH1A1 (0.60) | KMT2AMEN1CYP3A4POLBMAPT | |
| Hydrochloric Acid SCHEMBL27777744 | 0.80 | BAZ1A (0.59) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| Formaldehyde SCHEMBL27533960 | 0.79 | BAZ1A (0.58) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| Quinoline SCHEMBL28125811 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1MAPTKDM4ECYP1A2 | |
| Quinoline SCHEMBL9110133 | 0.77 | ALDH1A1 (0.66) | KMT2AMEN1POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705250-A1 | BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-04-10 | — | — | EP | disclosed |