Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | UTRN | P46939 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040818 | 0.89 | MAPT (0.52) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL9042363 | 0.82 | RAB9A (0.63) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL8037820 | 0.79 | MAPT (0.55) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL9042945 | 0.75 | DYRK1A (0.76) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL10751610 | 0.75 | KDR (0.51) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2243350 | 0.75 | RAB9A (0.65) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2740163 | 0.75 | MAPT (0.57) | MAPTALDH1A1TP53NPC1RAB9A | |
| SCHEMBL9041717 | 0.74 | STK33 (0.47) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2244509 | 0.74 | MAPT (0.79) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2740149 | 0.73 | MAPT (0.60) | MAPTALDH1A1TP53KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700906-A1 | Heterocyclic derivatives of N-phenylamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5496826-A | ANTICONVULSANTS, MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-03-05 | — | — | US | disclosed |