Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039279 | 0.87 | HPGD (0.41) | MAPTSMN1; SMN2KMT2APOLBCSF1R | |
| SCHEMBL9358761 | 0.80 | CSF1R (0.62) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8788590 | 0.80 | CSF1R (0.59) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9042136 | 0.80 | MEN1 (0.46) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9363080 | 0.79 | CSF1R (0.77) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9358714 | 0.78 | ALOX5 (0.51) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL6638162 | 0.76 | ALOX5 (0.51) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9140847 | 0.76 | CSF1R (0.54) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9363459 | 0.76 | CSF1R (0.59) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL16814374 | 0.74 | ALDH1A1 (0.51) | MAPTSMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472116-B1 | Thienopyridine Derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5256782-A | For anticholesterol agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5143919-A | Acyl-CoA:cholesterol acyltransferase inhibitors; anticholesterol agents; | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0472116-A1 | Thienopyridine Derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-02-26 | — | — | EP | disclosed |