Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044787 | 0.91 | AOC3 (0.42) | AOC3DHFR | |
| SCHEMBL28239209 | 0.79 | AOC3 (0.46) | AOC3DHFR | |
| SCHEMBL29687392 | 0.72 | ALDH1A1 (0.56) | PKMCYP2D6DHFR | |
| SCHEMBL28996034 | 0.72 | ALDH1A1 (0.56) | PKMCYP2D6DHFR | |
| SCHEMBL16486606 | 0.71 | AOC3 (0.42) | AOC3MEN1KMT2AHSD17B10 | |
| SCHEMBL22129318 | 0.70 | KMT2A (0.43) | MEN1KMT2ATDP1HSD17B10 | |
| Diphenylmethane SCHEMBL11159603 | 0.69 | MEN1 (0.67) | MEN1KMT2ATDP1PKMBCHE | |
| SCHEMBL28238100 | 0.68 | HTT (0.49) | MEN1KMT2A | |
| SCHEMBL21801032 | 0.67 | AOC3 (0.45) | AOC3CYP2D6 | |
| SCHEMBL28807545 | 0.67 | AOC3 (0.41) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708772-A1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002597-A1 | IMIDAZO[4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |