Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511056 | 0.93 | GNAO1 (0.44) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7508966 | 0.91 | GNAO1 (0.47) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7510266 | 0.90 | KDM4E (0.34) | HRH3ALDH1A1 | |
| SCHEMBL4736623 | 0.87 | LTA4H (0.45) | GNAI3GNAO1GNAI1 | |
| SCHEMBL7510250 | 0.87 | HRH3 (0.44) | GNAI3GNAO1GNAI1HRH3ALDH1A1 | |
| SCHEMBL19006951 | 0.82 | HRH3 (0.50) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL27553412 | 0.81 | HRH3 (0.54) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL651943 | 0.80 | GNAO1 (0.52) | GNAI3GNAO1GNAI1 | |
| SCHEMBL10924938 | 0.80 | HRH3 (0.44) | GNAI3GNAO1GNAI1HRH3ALDH1A1 | |
| SCHEMBL27540119 | 0.79 | HRH3 (0.58) | HRH3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551993-B1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5322952-A | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0551993-A1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |