Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 6/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786763 | 0.82 | CFTR (0.48) | CFTRCETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL10110458 | 0.81 | CETP (0.58) | CFTRCETP | |
| SCHEMBL904261 | 0.79 | CETP (0.49) | CFTRCETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL4070406 | 0.79 | CFTR (0.62) | CFTRESRRASMN1; SMN2KDM4EMAPT | |
| SCHEMBL904257 | 0.78 | CETP (0.45) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL31697102 | 0.78 | CFTR (0.51) | CFTRCETPESRRASMN1; SMN2KDM4E | |
| SCHEMBL22208882 | 0.78 | CFTR (0.51) | CFTRCETPESRRASMN1; SMN2KDM4E | |
| SCHEMBL29786833 | 0.76 | CFTR (0.47) | CFTRCETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL904254 | 0.76 | CETP (0.43) | CETPPTGDR2TBXA2RPTGDR | |
| SCHEMBL904259 | 0.74 | CETP (0.60) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |